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Learned features of antibody-antigen binding affinity

Defining predictors of antigen-binding affinity of antibodies is valuable for engineering therapeutic antibodies with high binding affinity to their targets. However, this task is challenging owing to the huge diversity in the conformations of the complementarity determining regions of antibodies an...

Повний опис

Бібліографічні деталі
Автори: Miller, Nathaniel L., Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
Формат: Online Стаття Текст
Мова:English
Опубліковано: Frontiers Media S.A. 2023
Предмети:
Онлайн доступ:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989197/
https://www.ncbi.nlm.nih.gov/pubmed/36895805
http://dx.doi.org/10.3389/fmolb.2023.1112738