Comparison of the efficacy and safety of leflunomide versus placebo combined with basic prednisone therapy in patients with active disease phase of Takayasu arteritis: study protocol for a randomized, double-blinded controlled trial (Takayasu arteritis clinical trial in China: TACTIC)

BACKGROUND: Takayasu arteritis (TAK) is an immune-induced granulomatous vasculitis that occurs primarily in young Asian women. Our previous cohort studies have indicated that leflunomide (LEF), which can lead to rapid induction and might be a promising alternative treatment for TAK. OBJECTIVES: To c...

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Detalles Bibliográficos
Autores principales: Sun, Ying, Wu, Bingjie, Zhang, Wei, Ma, Lili, Kong, Xiufang, Chen, Huiyong, Jiang, Lindi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989417/
https://www.ncbi.nlm.nih.gov/pubmed/36895331
http://dx.doi.org/10.1177/20406223231158567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989417/
https://www.ncbi.nlm.nih.gov/pubmed/36895331
http://dx.doi.org/10.1177/20406223231158567

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