The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms

Sulfolipid-1 (SL-1) is located in the Mycobacterium tuberculosis (M. tb) cell wall, and is essential for pathogen virulence and intracellular growth. Multiple proteins (e.g., Pks2, FadD23, PapA1, and MmpL8) in the SL-1 synthesis pathway can be treated as drug targets, but, to date, their structures...

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Detalles Bibliográficos
Autores principales: Yan, Mengrong, Cao, Lin, Zhao, Li, Zhou, Weihong, Liu, Xiang, Zhang, Wei, Rao, Zihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989471/
https://www.ncbi.nlm.nih.gov/pubmed/36896429
http://dx.doi.org/10.3389/fmicb.2023.1090534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989471/
https://www.ncbi.nlm.nih.gov/pubmed/36896429
http://dx.doi.org/10.3389/fmicb.2023.1090534

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