Cargando…

Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility

Variations in the composition of the intestinal bacterial microbiome correlate with acquisition of some sexually transmitted pathogens. To experimentally assess the contribution of intestinal dysbiosis to rectal lentiviral acquisition, we induce dysbiosis in rhesus macaques (RMs) with the antibiotic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortiz, Alexandra M., Baker, Phillip J., Langner, Charlotte A., Simpson, Jennifer, Stacy, Apollo, Flynn, Jacob K., Starke, Carly E., Vinton, Carol L., Fennessey, Christine M., Belkaid, Yasmine, Keele, Brandon F., Brenchley, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989505/
https://www.ncbi.nlm.nih.gov/pubmed/36848230
http://dx.doi.org/10.1016/j.celrep.2023.112020