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Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility
Variations in the composition of the intestinal bacterial microbiome correlate with acquisition of some sexually transmitted pathogens. To experimentally assess the contribution of intestinal dysbiosis to rectal lentiviral acquisition, we induce dysbiosis in rhesus macaques (RMs) with the antibiotic...
Autores principales: | Ortiz, Alexandra M., Baker, Phillip J., Langner, Charlotte A., Simpson, Jennifer, Stacy, Apollo, Flynn, Jacob K., Starke, Carly E., Vinton, Carol L., Fennessey, Christine M., Belkaid, Yasmine, Keele, Brandon F., Brenchley, Jason M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989505/ https://www.ncbi.nlm.nih.gov/pubmed/36848230 http://dx.doi.org/10.1016/j.celrep.2023.112020 |
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