Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer

Tumour-associated macrophages (TAMs) often promote cancer progression through immunosuppression in the tumour microenvironment (TME). However, the signalling pathways crosstalk responsible for this mechanism remain unclear. The aim of our study was to investigate whether the interaction between TAMs...

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Detalles Bibliográficos
Autores principales: Júnior, Raimundo Fernandes de Araújo, Lira, George A, Schomann, Timo, Cavalcante, Rômulo S, Vilar, Natalia Feitosa, de Paula, Regina Célia Monteiro, Gomes, Raelle Ferreira, Chung, Chih Kit, Jorquera-Cordero, Carla, Vepris, Olena, Chan, Alan B, Cruz, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989692/
https://www.ncbi.nlm.nih.gov/pubmed/36857852
http://dx.doi.org/10.1016/j.tranon.2023.101647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989692/
https://www.ncbi.nlm.nih.gov/pubmed/36857852
http://dx.doi.org/10.1016/j.tranon.2023.101647

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