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Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate

Many metabolites are generated in one step of a biochemical pathway and consumed in a subsequent step. Such metabolic intermediates are often reactive molecules which, if allowed to freely diffuse in the intracellular milieu, could lead to undesirable side reactions and even become toxic to the cell...

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Detalles Bibliográficos
Autores principales: Medina-Carmona, Encarnación, Gutierrez-Rus, Luis I, Manssour-Triedo, Fadia, Newton, Matilda S, Gamiz-Arco, Gloria, Mota, Antonio J, Reiné, Pablo, Cuerva, Juan Manuel, Ortega-Muñoz, Mariano, Andrés-León, Eduardo, Ortega-Roldan, Jose Luis, Seelig, Burckhard, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989741/
https://www.ncbi.nlm.nih.gov/pubmed/36788592
http://dx.doi.org/10.1093/molbev/msad032