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Single-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control

The chromatin environment at origins of replication is thought to influence DNA replication initiation in eukaryotic genomes. However, it remains unclear how and which chromatin features control the firing of early-efficient (EE) or late-inefficient (LI) origins. Here, we use site-specific recombina...

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Detalles Bibliográficos
Autores principales: Weiβ, Matthias, Chanou, Anna, Schauer, Tamas, Tvardovskiy, Andrey, Meiser, Stefan, König, Ann-Christine, Schmidt, Tobias, Kruse, Elisabeth, Ummethum, Henning, Trauner, Manuel, Werner, Marcel, Lalonde, Maxime, Hauck, Stefanie M., Scialdone, Antonio, Hamperl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989823/
https://www.ncbi.nlm.nih.gov/pubmed/36701236
http://dx.doi.org/10.1016/j.celrep.2023.112045