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Single-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control
The chromatin environment at origins of replication is thought to influence DNA replication initiation in eukaryotic genomes. However, it remains unclear how and which chromatin features control the firing of early-efficient (EE) or late-inefficient (LI) origins. Here, we use site-specific recombina...
Autores principales: | Weiβ, Matthias, Chanou, Anna, Schauer, Tamas, Tvardovskiy, Andrey, Meiser, Stefan, König, Ann-Christine, Schmidt, Tobias, Kruse, Elisabeth, Ummethum, Henning, Trauner, Manuel, Werner, Marcel, Lalonde, Maxime, Hauck, Stefanie M., Scialdone, Antonio, Hamperl, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989823/ https://www.ncbi.nlm.nih.gov/pubmed/36701236 http://dx.doi.org/10.1016/j.celrep.2023.112045 |
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