Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice

Genome‐wide association studies have linked the ORM (yeast)–like protein isoform 3 (ORMDL3) to asthma severity. Although ORMDL3 is a member of a family that negatively regulates serine palmitoyltransferase (SPT) and thus biosynthesis of sphingolipids, it is still unclear whether ORMDL3 and altered s...

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Detalles Bibliográficos
Autores principales: James, Briana N., Weigel, Cynthia, Green, Christopher D., Brown, Ryan D. R., Palladino, Elisa N. D., Tharakan, Anuj, Milstien, Sheldon, Proia, Richard L., Martin, Rebecca K., Spiegel, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990076/
https://www.ncbi.nlm.nih.gov/pubmed/36753412
http://dx.doi.org/10.1096/fj.202201821R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990076/
https://www.ncbi.nlm.nih.gov/pubmed/36753412
http://dx.doi.org/10.1096/fj.202201821R

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