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Somatic mutation landscape in a cohort of meningiomas that have undergone grade progression

BACKGROUND: A subset of meningiomas progress in histopathological grade but drivers of progression are poorly understood. We aimed to identify somatic mutations and copy number alterations (CNAs) associated with grade progression in a unique matched tumour dataset. METHODS: Utilising a prospective d...

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Detalles Bibliográficos
Autores principales: Cain, Sarah A, Pope, Bernard, Mangiola, Stefano, Mantamadiotis, Theo, Drummond, Katharine J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990218/
https://www.ncbi.nlm.nih.gov/pubmed/36882706
http://dx.doi.org/10.1186/s12885-023-10624-9