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Eip74EF is a dominant modifier for ALS-FTD-linked VCP(R152H) phenotypes in the Drosophila eye model

OBJECTIVES: In 2012, Liu et al. reported that miR-34 is an age-related miRNA regulating age-associated events and long-term brain integrity in Drosophila. They demonstrated that modulating miR-34 and its downstream target, Eip74EF, showed beneficial effects on an age-related disease using a Drosophi...

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Detalles Bibliográficos
Autores principales: Chalmers, Madeleine R., Kim, JiHye, Kim, Nam Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990252/
https://www.ncbi.nlm.nih.gov/pubmed/36879317
http://dx.doi.org/10.1186/s13104-023-06297-z