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Properties of Nav1.8(ChR2)-positive and Nav1.8(ChR2)-negative afferent mechanoreceptors in the hindpaw glabrous skin of mice

Nav1.8-positive afferent fibers are mostly nociceptors playing a role in mediating thermal and mechanical pain, but mechanoreceptors within these afferents have not been fully investigated. In this study, we generated mice expressing channel rhodopsin 2 (ChR2) in Nav1.8-positive afferents (Nav1.8(Ch...

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Detalles Bibliográficos
Autores principales: Yamada, Akihiro, Yamada, Ayaka I., Ling, Jennifer, Furue, Hidemasa, Luo, Wenqin, Gu, Jianguo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990257/
https://www.ncbi.nlm.nih.gov/pubmed/36882762
http://dx.doi.org/10.1186/s13041-023-01015-z