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Gene regulation network inference using k-nearest neighbor-based mutual information estimation: revisiting an old DREAM

BACKGROUND: A cell exhibits a variety of responses to internal and external cues. These responses are possible, in part, due to the presence of an elaborate gene regulatory network (GRN) in every single cell. In the past 20 years, many groups worked on reconstructing the topological structure of GRN...

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Detalles Bibliográficos
Autores principales: Shachaf, Lior I., Roberts, Elijah, Cahan, Patrick, Xiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990267/
https://www.ncbi.nlm.nih.gov/pubmed/36879188
http://dx.doi.org/10.1186/s12859-022-05047-5