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Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury

BACKGROUND: Sepsis-associated AKI has been shown to be related to sepsis mortality. Macrophage activation and endothelial cell damage are involved in the progression of sepsis-associated AKI, but the specific mechanisms are still unclear. METHODS: In vitro experiments, exosomes extracted from lipopo...

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Detalles Bibliográficos
Autores principales: Xiang, Huiling, Xu, Zhifeng, Zhang, Chun, Xiong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990300/
https://www.ncbi.nlm.nih.gov/pubmed/36879272
http://dx.doi.org/10.1186/s13578-023-00990-z