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Propensity scores as a novel method to guide sample allocation and minimize batch effects during the design of high throughput experiments

BACKGROUND: We developed a novel approach to minimize batch effects when assigning samples to batches. Our algorithm selects a batch allocation, among all possible ways of assigning samples to batches, that minimizes differences in average propensity score between batches. This strategy was compared...

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Detalles Bibliográficos
Autores principales: Carry, Patrick M., Vigers, Tim, Vanderlinden, Lauren A., Keeter, Carson, Dong, Fran, Buckner, Teresa, Litkowski, Elizabeth, Yang, Ivana, Norris, Jill M., Kechris, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990331/
https://www.ncbi.nlm.nih.gov/pubmed/36882691
http://dx.doi.org/10.1186/s12859-023-05202-6