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Propensity scores as a novel method to guide sample allocation and minimize batch effects during the design of high throughput experiments
BACKGROUND: We developed a novel approach to minimize batch effects when assigning samples to batches. Our algorithm selects a batch allocation, among all possible ways of assigning samples to batches, that minimizes differences in average propensity score between batches. This strategy was compared...
Autores principales: | Carry, Patrick M., Vigers, Tim, Vanderlinden, Lauren A., Keeter, Carson, Dong, Fran, Buckner, Teresa, Litkowski, Elizabeth, Yang, Ivana, Norris, Jill M., Kechris, Katerina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990331/ https://www.ncbi.nlm.nih.gov/pubmed/36882691 http://dx.doi.org/10.1186/s12859-023-05202-6 |
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