TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury

BACKGROUND: Necroptosis of macrophages is a necessary element in reinforcing intrapulmonary inflammation during acute lung injury (ALI). However, the molecular mechanism that sparks macrophage necroptosis is still unclear. Triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recogn...

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Detalles Bibliográficos
Autores principales: Zhong, Wen-Jing, Zhang, Jun, Duan, Jia-Xi, Zhang, Chen-Yu, Ma, Sheng-Chao, Li, Yu-Sheng, Yang, Nan-Shi-Yu, Yang, Hui-Hui, Xiong, Jian-Bing, Guan, Cha-Xiang, Jiang, Zhi-Xing, You, Zhi-Jian, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990355/
https://www.ncbi.nlm.nih.gov/pubmed/36879273
http://dx.doi.org/10.1186/s12967-023-04027-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990355/
https://www.ncbi.nlm.nih.gov/pubmed/36879273
http://dx.doi.org/10.1186/s12967-023-04027-4

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