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TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury

BACKGROUND: Necroptosis of macrophages is a necessary element in reinforcing intrapulmonary inflammation during acute lung injury (ALI). However, the molecular mechanism that sparks macrophage necroptosis is still unclear. Triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recogn...

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Detalles Bibliográficos
Autores principales:	Zhong, Wen-Jing, Zhang, Jun, Duan, Jia-Xi, Zhang, Chen-Yu, Ma, Sheng-Chao, Li, Yu-Sheng, Yang, Nan-Shi-Yu, Yang, Hui-Hui, Xiong, Jian-Bing, Guan, Cha-Xiang, Jiang, Zhi-Xing, You, Zhi-Jian, Zhou, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990355/ https://www.ncbi.nlm.nih.gov/pubmed/36879273 http://dx.doi.org/10.1186/s12967-023-04027-4

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