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Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies

Endemic Burkitt lymphoma (BL) is a childhood cancer in sub-Saharan Africa characterized by Epstein–Barr virus and malaria-associated aberrant B-cell activation and MYC chromosomal translocation. Survival rates hover at 50% after conventional chemotherapies; therefore, clinically relevant models are...

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Detalles Bibliográficos
Autores principales: Saikumar Lakshmi, Priya, Oduor, Cliff I, Forconi, Catherine S, M’Bana, Viriato, Bly, Courtney, Gerstein, Rachel M, Otieno, Juliana A, Ong’echa, John M, Münz, Christian, Luftig, Micah A, Brehm, Michael A, Bailey, Jeffrey A, Moormann, Ann M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990458/
https://www.ncbi.nlm.nih.gov/pubmed/36878637
http://dx.doi.org/10.26508/lsa.202101355