Comparison of vector elements and process conditions in transient and stable suspension HEK293 platforms using SARS-CoV-2 receptor binding domain as a model protein

BACKGROUND: Mammalian cell lines are frequently used as protein expression hosts because of their ability to correctly fold and assemble complex proteins, produce them at high titers, and confer post-translational modifications (PTMs) critical to proper function. Increasing demand for proteins with...

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Detalles Bibliográficos
Autores principales: Green, Erica A., Hamaker, Nathaniel K., Lee, Kelvin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990576/
https://www.ncbi.nlm.nih.gov/pubmed/36882740
http://dx.doi.org/10.1186/s12896-023-00777-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990576/
https://www.ncbi.nlm.nih.gov/pubmed/36882740
http://dx.doi.org/10.1186/s12896-023-00777-7

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