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HNF1A regulates oxaliplatin resistance in pancreatic cancer by targeting 53BP1

DNA double-strand break repair is critically involved in oxaliplatin resistance in pancreatic ductal adenocarcinoma (PDAC). Hepatocyte nuclear factor 1 homeobox A (HNF1A) has received increased attention regarding its role in cancer progression. The present study explored the role of HNF1A in oxalip...

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Detalles Bibliográficos
Autores principales: Xia, Renpeng, Hu, Chonghui, Ye, Yuancheng, Zhang, Xiang, Li, Tingting, He, Rihua, Zheng, Shangyou, Wen, Xiaofeng, Chen, Rufu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990585/
https://www.ncbi.nlm.nih.gov/pubmed/36825600
http://dx.doi.org/10.3892/ijo.2023.5493