Insulin-like growth factor 1 reduces coronary atherosclerosis in pigs with familial hypercholesterolemia

Although murine models of coronary atherosclerotic disease have been used extensively to determine mechanisms, limited new therapeutic options have emerged. Pigs with familial hypercholesterolemia (FH pigs) develop complex coronary atheromas that are almost identical to human lesions. We reported pr...

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Detalles Bibliográficos
Autores principales: Sukhanov, Sergiy, Higashi, Yusuke, Yoshida, Tadashi, Danchuk, Svitlana, Alfortish, Mitzi, Goodchild, Traci, Scarborough, Amy, Sharp, Thomas, Jenkins, James S., Garcia, Daniel, Ivey, Jan, Tharp, Darla L., Schumacher, Jeffrey, Rozenbaum, Zach, Kolls, Jay K., Bowles, Douglas, Lefer, David, Delafontaine, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990768/
https://www.ncbi.nlm.nih.gov/pubmed/36602878
http://dx.doi.org/10.1172/jci.insight.165713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990768/
https://www.ncbi.nlm.nih.gov/pubmed/36602878
http://dx.doi.org/10.1172/jci.insight.165713

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