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Insulin-like growth factor 1 reduces coronary atherosclerosis in pigs with familial hypercholesterolemia
Although murine models of coronary atherosclerotic disease have been used extensively to determine mechanisms, limited new therapeutic options have emerged. Pigs with familial hypercholesterolemia (FH pigs) develop complex coronary atheromas that are almost identical to human lesions. We reported pr...
Autores principales: | Sukhanov, Sergiy, Higashi, Yusuke, Yoshida, Tadashi, Danchuk, Svitlana, Alfortish, Mitzi, Goodchild, Traci, Scarborough, Amy, Sharp, Thomas, Jenkins, James S., Garcia, Daniel, Ivey, Jan, Tharp, Darla L., Schumacher, Jeffrey, Rozenbaum, Zach, Kolls, Jay K., Bowles, Douglas, Lefer, David, Delafontaine, Patrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990768/ https://www.ncbi.nlm.nih.gov/pubmed/36602878 http://dx.doi.org/10.1172/jci.insight.165713 |
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