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Novel insights in the pathomechanism of Brugada syndrome and fever‐related type 1 ECG changes in a preclinical study using human‐induced pluripotent stem cell‐derived cardiomyocytes

BACKGROUND: Brugada syndrome (BrS) is causing sudden cardiac death (SCD) mainly at young age. Studying the underlying mechanisms associated with BrS type I electrocardiogram (ECG) changes in the presence of fever and roles of autophagy for BrS remains lacking. OBJECTIVES: We sought to study the path...

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Detalles Bibliográficos
Autores principales: Li, Yingrui, Dinkel, Hendrik, Pakalniskyte, Dalia, Busley, Alexandra Viktoria, Cyganek, Lukas, Zhong, Rujia, Zhang, Feng, Xu, Qiang, Maywald, Lasse, Aweimer, Assem, Huang, Mengying, Liao, Zhenxing, Meng, Zenghui, Yan, Chen, Prädel, Timo, Rose, Lena, Moscu‐Gregor, Alexander, Hohn, Alyssa, Yang, Zhen, Qiao, Lin, Mügge, Andreas, Zhou, Xiaobo, Akin, Ibrahim, El‐Battrawy, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990896/
https://www.ncbi.nlm.nih.gov/pubmed/36881552
http://dx.doi.org/10.1002/ctm2.1130