Local delivery of FK506 to a nerve allograft is comparable to systemic delivery at suppressing allogeneic graft rejection

The objective of this study was to determine if locally delivered FK506 could prevent allogeneic nerve graft rejection long enough to allow axon regeneration to pass through the nerve graft. An 8mm mouse sciatic nerve gap injury repaired with a nerve allograft was used to assess the effectiveness of...

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Detalles Bibliográficos
Autores principales: Davis, Brett, Wojtalewicz, Susan, Erickson, Sierra, Veith, Jacob, Simpson, Andrew, Sant, Himanshu, Shea, Jill, Gale, Bruce, Agarwal, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990949/
https://www.ncbi.nlm.nih.gov/pubmed/36881592
http://dx.doi.org/10.1371/journal.pone.0281911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990949/
https://www.ncbi.nlm.nih.gov/pubmed/36881592
http://dx.doi.org/10.1371/journal.pone.0281911

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