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Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations

Polygenic scores (PGS) can identify individuals at risk of adverse health events and guide genetics-based personalized medicine. However, it is not clear how well PGS translate between different populations, limiting their application to well-studied ethnicities. Proteins are intermediate traits lin...

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Detalles Bibliográficos
Autores principales: Thareja, Gaurav, Belkadi, Aziz, Arnold, Matthias, Albagha, Omar M E, Graumann, Johannes, Schmidt, Frank, Grallert, Harald, Peters, Annette, Gieger, Christian, Consortium, The Qatar Genome Program Research, Suhre, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990988/
https://www.ncbi.nlm.nih.gov/pubmed/36168886
http://dx.doi.org/10.1093/hmg/ddac243