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A171 INTESTINAL INTERFERON-LAMBDA RECEPTOR 1 EXPRESSION AND RESPONSES ARE SIGNIFICANTLY DECREASED IN PEDIATRIC INFLAMMATORY BOWEL DISEASE PATIENTS

BACKGROUND: While interferon-lambdas (IFN-λs) were initially discovered for their role in antiviral immunity at mucosal barriers such as the lung and gut, there are many unanswered questions for how IFN-λs uniquely dampen inflammatory immune responses. In mouse colitis models, IFN-λs were shown to p...

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Detalles Bibliográficos
Autores principales: Ogungbola, O, Mahmood, R, Bittorf, K, Nguyen, N, El-Matary, W, Wine, E, Tyrrell, L, Armstrong, H, Santer, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991124/
http://dx.doi.org/10.1093/jcag/gwac036.171