Prophylactic intranasal administration of lipid nanoparticle formulated siRNAs reduce SARS-CoV-2 and RSV lung infection

RNA interference (RNAi) is an emerging and promising therapy for a wide range of respiratory viral infections. This highly specific suppression can be achieved by the introduction of short-interfering RNA (siRNA) into mammalian systems, resulting in the effective reduction of viral load. Unfortunate...

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Detalles Bibliográficos
Autores principales: Supramaniam, Aroon, Tayyar, Yaman, Clarke, Daniel T.W., Kelly, Gabrielle, Acharya, Dhruba, Morris, Kevin V., McMillan, Nigel A.J., Idris, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991324/
https://www.ncbi.nlm.nih.gov/pubmed/36934064
http://dx.doi.org/10.1016/j.jmii.2023.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991324/
https://www.ncbi.nlm.nih.gov/pubmed/36934064
http://dx.doi.org/10.1016/j.jmii.2023.02.010

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