A29 HIGH DIMENSIONAL SINGLE CELL ANALYSIS OF IL-4 TREATED MACROPHAGES REVEALS A HETEROGENIC PHENOTYPE AND THE ABSENCE OF CD206+ SUBSETS IN CROHN'S DISEASE PATIENTS

BACKGROUND: Individuals with IBD have a reduced quality of life and while treatment has improved, a cure remains elusive. Interleukin-4 differentiated macrophages (M(IL4)s) from healthy donors and IBD patients in remission promote epithelial wound repair and reduce the severity of colitis in a mouse...

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Detalles Bibliográficos
Autores principales: Callejas, B E, Flanigan, K, Schlechte, J, Sousa, J A, Wang, A, McDonald, B, Paniconne, R, McKay, D M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Poster of Distinction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991349/
http://dx.doi.org/10.1093/jcag/gwac036.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991349/
http://dx.doi.org/10.1093/jcag/gwac036.029

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