A21 ROLE OF SIALIC ACID O-ACETYLATION IN MAINTAINING MUCUS INTEGRITY AND HOMEOSTASIS OF THE COLONIC MUCOSA

BACKGROUND: The mucus network provides innate immune defense to protect our gastrointestinal tract from pathogens, and promote homeostasis with our resident microbiota. This network is constituted by the mucin MUC2 (Muc2 in mouse), which is ~80% complex O-linked glycans by weight. Sialic acid (Sia)...

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Detalles Bibliográficos
Autores principales: Jafaripour, S, Melvin, M, Olsson, H, Parrish, C, Wasik, B, Zandberg, W, Bergstrom, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Poster of Distinction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991361/
http://dx.doi.org/10.1093/jcag/gwac036.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991361/
http://dx.doi.org/10.1093/jcag/gwac036.021

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