The function of lactate dehydrogenase A in retinal neurons: implications to retinal degenerative diseases

The postmitotic retina is highly metabolic and the photoreceptors depend on aerobic glycolysis for an energy source and cellular anabolic activities. Lactate dehydrogenase A (LDHA) is a key enzyme in aerobic glycolysis, which converts pyruvate to lactate. Here we show that cell-type-specific activel...

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Detalles Bibliográficos
Autores principales: Rajala, Ammaji, Bhat, Mohd A, Teel, Kenneth, Gopinadhan Nair, Gopa Kumar, Purcell, Lindsey, Rajala, Raju V S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991461/
https://www.ncbi.nlm.nih.gov/pubmed/36896135
http://dx.doi.org/10.1093/pnasnexus/pgad038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991461/
https://www.ncbi.nlm.nih.gov/pubmed/36896135
http://dx.doi.org/10.1093/pnasnexus/pgad038

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