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The function of lactate dehydrogenase A in retinal neurons: implications to retinal degenerative diseases

The postmitotic retina is highly metabolic and the photoreceptors depend on aerobic glycolysis for an energy source and cellular anabolic activities. Lactate dehydrogenase A (LDHA) is a key enzyme in aerobic glycolysis, which converts pyruvate to lactate. Here we show that cell-type-specific activel...

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Detalles Bibliográficos
Autores principales:	Rajala, Ammaji, Bhat, Mohd A, Teel, Kenneth, Gopinadhan Nair, Gopa Kumar, Purcell, Lindsey, Rajala, Raju V S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Biological, Health, and Medical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991461/ https://www.ncbi.nlm.nih.gov/pubmed/36896135 http://dx.doi.org/10.1093/pnasnexus/pgad038

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