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Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells

INTRODUCTION: Along with blood glucose levels, diabetic retinopathy (DR) development also involves endogenous risk factors, such as trimethylamine-N-oxide (TMAO), a product of intestinal flora metabolic disorder, which exacerbates diabetic microvascular complications. However, the effect of TMAO on...

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Detalles Bibliográficos
Autores principales: Xue, Lidan, Huang, Lili, Tian, Yajing, Cao, Xin, Song, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991475/
https://www.ncbi.nlm.nih.gov/pubmed/36895266
http://dx.doi.org/10.1155/2023/8224752