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Massively parallel identification of mRNA localization elements in primary cortical neurons

Cells adopt highly polarized shapes and form distinct subcellular compartments in many cases due to the localization of many mRNAs to specific areas, where they are translated into proteins with local functions. This mRNA localization is mediated by specific cis-regulatory elements in mRNAs, commonl...

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Detalles Bibliográficos
Autores principales: Mendonsa, Samantha, von Kügelgen, Nicolai, Dantsuji, Sayaka, Ron, Maya, Breimann, Laura, Baranovskii, Artem, Lödige, Inga, Kirchner, Marieluise, Fischer, Meret, Zerna, Nadja, Bujanic, Lucija, Mertins, Philipp, Ulitsky, Igor, Chekulaeva, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991926/
https://www.ncbi.nlm.nih.gov/pubmed/36646877
http://dx.doi.org/10.1038/s41593-022-01243-x