Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice

Even with extensive transfusion support, trauma-induced bleeding often leads to death. Early intervention may improve outcomes, yet which blood products, factor concentrates, or other drugs constitute optimal treatment is unclear. Patients with acute traumatic coagulopathy (ATC), arising from trauma...

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Detalles Bibliográficos
Autores principales: Eltringham-Smith, Louise J., Meixner, Scott C., Pryzdial, Edward L. G., Sheffield, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992365/
https://www.ncbi.nlm.nih.gov/pubmed/36882463
http://dx.doi.org/10.1038/s41598-023-30794-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992365/
https://www.ncbi.nlm.nih.gov/pubmed/36882463
http://dx.doi.org/10.1038/s41598-023-30794-7

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