Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisib

Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma that is incurable with existing therapies, and therefore presents a significant unmet clinical need. The ability of this disease to overcome therapy, including those that target the B cell receptor pathway which has a pathogenic...

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Detalles Bibliográficos
Autores principales: Till, Kathleen J., Abdullah, Mariah, Alnassfan, Tahera, Janet, Gallardo Zapata, Marks, Thomas, Coma, Silvia, Weaver, David T., Pachter, Jonathan A., Pettitt, Andrew R., Slupsky, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992372/
https://www.ncbi.nlm.nih.gov/pubmed/36882482
http://dx.doi.org/10.1038/s41598-023-30148-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992372/
https://www.ncbi.nlm.nih.gov/pubmed/36882482
http://dx.doi.org/10.1038/s41598-023-30148-3

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