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CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes

In this study, we identified that a conserved circular RNA (circRNA) DICAR, which was downregulated in diabetic mouse hearts. DICAR had an inhibitory effect on diabetic cardiomyopathy (DCM), as the spontaneous cardiac dysfunction, cardiac cell hypertrophy, and cardiac fibrosis occurred in DICAR defi...

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Detalles Bibliográficos
Autores principales: Yuan, Qiong, Sun, Yunwei, Yang, Fan, Yan, Dan, Shen, Meihua, Jin, Zhigang, Zhan, Lin, Liu, Guangqi, Yang, Ling, Zhou, Qianyi, Yu, Zhijun, Zhou, Xiangyu, Yu, Yang, Xu, Yong, Wu, Qingming, Luo, Jianfang, Hu, Xiamin, Zhang, Chunxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992392/
https://www.ncbi.nlm.nih.gov/pubmed/36882410
http://dx.doi.org/10.1038/s41392-022-01306-2