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ACSL1-induced ferroptosis and platinum resistance in ovarian cancer by increasing FSP1 N-myristylation and stability

Reprogramming of lipid metabolism, which modulates energy utilization and cell signaling, maintains cell survival and promotes cancer metastasis in cancer cells. Ferroptosis is a type of cell necrosis caused by an overload of lipid oxidation, which has been demonstrated to be involved in cancer cell...

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Detalles Bibliográficos
Autores principales: Zhang, Qingyu, Li, Ning, Deng, Limei, Jiang, Xingmei, Zhang, Yuming, Lee, Leo Tsz On, Zhang, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992462/
https://www.ncbi.nlm.nih.gov/pubmed/36882396
http://dx.doi.org/10.1038/s41420-023-01385-2