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Extensive MHC class IIβ diversity across multiple loci in the small-spotted catshark (Scyliorhinus canicula)

The major histocompatibility complex (MHC) is a multigene family responsible for pathogen detection, and initiation of adaptive immune responses. Duplication, natural selection, recombination, and their resulting high functional genetic diversity spread across several duplicated loci are the main ha...

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Detalles Bibliográficos
Autores principales: Gaigher, Arnaud, Rota, Alessia, Neves, Fabiana, Muñoz-Mérida, Antonio, Blasco-Aróstegui, Javier, Almeida, Tereza, Veríssimo, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992475/
https://www.ncbi.nlm.nih.gov/pubmed/36882519
http://dx.doi.org/10.1038/s41598-023-30876-6