Two-step structural changes in M3 muscarinic receptor activation rely on the coupled G(q) protein cycle

G protein-coupled receptors (GPCRs) regulate diverse intracellular signaling pathways through the activation of heterotrimeric G proteins. However, the effects of the sequential activation–deactivation cycle of G protein on the conformational changes of GPCRs remains unknown. By developing a Förster...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Yong-Seok, Yeon, Jun-Hee, Ko, Woori, Suh, Byung-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992711/
https://www.ncbi.nlm.nih.gov/pubmed/36882424
http://dx.doi.org/10.1038/s41467-023-36911-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992711/
https://www.ncbi.nlm.nih.gov/pubmed/36882424
http://dx.doi.org/10.1038/s41467-023-36911-4

Ejemplares similares