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BATF sustains homeostasis and functionality of bone marrow Treg cells to preserve homeostatic regulation of hematopoiesis and development of B cells

Bone marrow Treg cells (BM Tregs) orchestrate stem cell niches crucial for hematopoiesis. Yet little is known about the molecular mechanisms governing BM Treg homeostasis and function. Here we report that the transcription factor BATF maintains homeostasis and functionality of BM Tregs to facilitate...

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Detalles Bibliográficos
Autores principales: Tikka, Chiranjeevi, Beasley, Lindsay, Xu, Chengxian, Yang, Jing, Cooper, Scott, Lechner, Joseph, Gutch, Sarah, Kaplan, Mark H., Capitano, Maegan, Yang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992736/
https://www.ncbi.nlm.nih.gov/pubmed/36911703
http://dx.doi.org/10.3389/fimmu.2023.1026368