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Intraluminal pressure elevates intracellular calcium and contracts CNS pericytes: Role of voltage-dependent calcium channels

Arteriolar smooth muscle cells (SMCs) and capillary pericytes dynamically regulate blood flow in the central nervous system in the face of fluctuating perfusion pressures. Pressure-induced depolarization and Ca(2+) elevation provide a mechanism for regulation of SMC contraction, but whether pericyte...

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Detalles Bibliográficos
Autores principales: Klug, Nicholas R., Sancho, Maria, Gonzales, Albert L., Heppner, Thomas J., O’Brien, Rochelle Irene C., Hill-Eubanks, David, Nelson, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992766/
https://www.ncbi.nlm.nih.gov/pubmed/36802432
http://dx.doi.org/10.1073/pnas.2216421120