Mammalian telomeric RNA (TERRA) can be translated to produce valine–arginine and glycine–leucine dipeptide repeat proteins

Mammalian telomeres consist of (TTAGGG)n repeats. Transcription of the C-rich strand generates a G-rich RNA, termed TERRA, containing G-quadruplex structures. Recent discoveries in several human nucleotide expansion diseases revealed that RNA transcripts containing long runs of 3 or 6 nt repeats whi...

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Detalles Bibliográficos
Autores principales: Al-Turki, Taghreed M., Griffith, Jack D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992779/
https://www.ncbi.nlm.nih.gov/pubmed/36812212
http://dx.doi.org/10.1073/pnas.2221529120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992779/
https://www.ncbi.nlm.nih.gov/pubmed/36812212
http://dx.doi.org/10.1073/pnas.2221529120

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