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PASSED: Brain atrophy in non-demented individuals in a long-term longitudinal study from two independent cohorts

INTRODUCTION: Alzheimer’s disease (AD) is indicated by a decrease in amyloid beta 42 (Aβ42) level or the Aβ42/Aβ40 ratio, and by increased levels of Tau with phosphorylated threonine at position 181 (pTau181) in cerebrospinal fluid (CSF) years before the onset of clinical symptoms. However, once onl...

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Detalles Bibliográficos
Autores principales: Haas, Anna-Lena, Olm, Pauline, Utz, Janine, Siegmann, Eva-Maria, Spitzer, Philipp, Florvaag, Anna, Schmidt, Manuel Alexander, Doerfler, Arnd, Lewczuk, Piotr, Kornhuber, Johannes, Maler, Juan Manuel, Oberstein, Timo Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992803/
https://www.ncbi.nlm.nih.gov/pubmed/36909947
http://dx.doi.org/10.3389/fnagi.2023.1121500