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PASSED: Brain atrophy in non-demented individuals in a long-term longitudinal study from two independent cohorts
INTRODUCTION: Alzheimer’s disease (AD) is indicated by a decrease in amyloid beta 42 (Aβ42) level or the Aβ42/Aβ40 ratio, and by increased levels of Tau with phosphorylated threonine at position 181 (pTau181) in cerebrospinal fluid (CSF) years before the onset of clinical symptoms. However, once onl...
Autores principales: | Haas, Anna-Lena, Olm, Pauline, Utz, Janine, Siegmann, Eva-Maria, Spitzer, Philipp, Florvaag, Anna, Schmidt, Manuel Alexander, Doerfler, Arnd, Lewczuk, Piotr, Kornhuber, Johannes, Maler, Juan Manuel, Oberstein, Timo Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992803/ https://www.ncbi.nlm.nih.gov/pubmed/36909947 http://dx.doi.org/10.3389/fnagi.2023.1121500 |
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