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Peptide-binding specificity prediction using fine-tuned protein structure prediction networks

Peptide-binding proteins play key roles in biology, and predicting their binding specificity is a long-standing challenge. While considerable protein structural information is available, the most successful current methods use sequence information alone, in part because it has been a challenge to mo...

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Detalles Bibliográficos
Autores principales: Motmaen, Amir, Dauparas, Justas, Baek, Minkyung, Abedi, Mohamad H., Baker, David, Bradley, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992841/
https://www.ncbi.nlm.nih.gov/pubmed/36802421
http://dx.doi.org/10.1073/pnas.2216697120