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A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products

The enediynes are structurally characterized by a 1,5-diyne-3-ene motif within a 9- or 10-membered enediyne core. The anthraquinone-fused enediynes (AFEs) are a subclass of 10-membered enediynes that contain an anthraquinone moiety fused to the enediyne core as exemplified by dynemicins and tiancimy...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Minakshi, Cui, Zheng, Daniel Hankore, Erome, Moonschi, Faruk H., Saghaeiannejad Esfahani, Hoda, Kalkreuter, Edward, Gui, Chun, Yang, Dong, Phillips, George N., Thorson, Jon S., Shen, Ben, Van Lanen, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992847/
https://www.ncbi.nlm.nih.gov/pubmed/36802426
http://dx.doi.org/10.1073/pnas.2220468120