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A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products
The enediynes are structurally characterized by a 1,5-diyne-3-ene motif within a 9- or 10-membered enediyne core. The anthraquinone-fused enediynes (AFEs) are a subclass of 10-membered enediynes that contain an anthraquinone moiety fused to the enediyne core as exemplified by dynemicins and tiancimy...
Autores principales: | Bhardwaj, Minakshi, Cui, Zheng, Daniel Hankore, Erome, Moonschi, Faruk H., Saghaeiannejad Esfahani, Hoda, Kalkreuter, Edward, Gui, Chun, Yang, Dong, Phillips, George N., Thorson, Jon S., Shen, Ben, Van Lanen, Steven G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992847/ https://www.ncbi.nlm.nih.gov/pubmed/36802426 http://dx.doi.org/10.1073/pnas.2220468120 |
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