Drosophila hedgehog signaling range and robustness depend on direct and sustained heparan sulfate interactions

Morphogens determine cellular differentiation in many developing tissues in a concentration dependent manner. As a central model for gradient formation during animal development, Hedgehog (Hh) morphogens spread away from their source to direct growth and pattern formation in the Drosophila wing disc...

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Detalles Bibliográficos
Autores principales: Manikowski, Dominique, Steffes, Georg, Froese, Jurij, Exner, Sebastian, Ehring, Kristina, Gude, Fabian, Di Iorio, Daniele, Wegner, Seraphine V., Grobe, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992881/
https://www.ncbi.nlm.nih.gov/pubmed/36911531
http://dx.doi.org/10.3389/fmolb.2023.1130064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992881/
https://www.ncbi.nlm.nih.gov/pubmed/36911531
http://dx.doi.org/10.3389/fmolb.2023.1130064

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